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대학소개 SNU Awards
학술연구교육상(연구부문)
SNU Awards
학술연구교육상(연구부문)
홍성철 교수
교육
연도 | 내용 |
---|---|
1994 | 서울대학교 물리학 학사 |
1996 | 서울대학교 물리학 석사 |
2000 | 서울대학교 물리학 박사 |
2000 ~ 2001 | 서울대학교 박사후연구원 |
2002 ~ 2006 | 일리노이대학교(UIUC) 박사후연구원 |
2006 ~ 현재 | 서울대 물리천문학부 교수 |
주요 연구분야
단일분자 생물물리학
대표 연구성과
- "DNA cleavage and opening reactions of human topoisomerase IIα are regulated via Mg2+-mediated dynamic bending of gate-DNA", PNAS (2012).
- "Hidden complexity in the isomerization dynamics of Holliday junctions", Nat Chem. (2012).
- "Kinetic mechanism for viral dsRNA length discrimination by MDA5 filaments", PNAS (2012).
- "A single-molecule dissection of ligand binding to a protein with intrinsic dynamics", Nat Chem Biol. (2013).
- "Maximizing information content of single-molecule FRET experiments: multi-color FRET and FRET combined with force or torque", Chem Soc Rev. (2014).
- "Sub-diffraction limit imaging of inorganic nanowire networks interfacing cells", Small. (2014).
- "Dynamic anchoring of the 3'-end of the guide strand controls the target dissociation of Argonaute-guide complex", J Am Chem Soc. (2013).
- "An optical trap combined with three-color FRET", J Am Chem Soc. (2013).
- "Protein conformational dynamics dictate the binding affinity for a ligand", Nat Commun. (2014).
- "Functional Anatomy of the Human Microprocessor", Cell. (2015).
- "Human Argonaute 2 Has Diverse Reaction Pathways on Target RNAs" Mol Cell. (2015).
- "AUF1 promotes let-7b loading on Argonaute 2", Genes Dev. (2015).
- "Structure of Human DROSHA", Cell (2016).
- "AUF1 facilitates microRNA-mediated gene silencing", Nucleic Acids Research (2017).
- "NAP1L1 accelerates activation and decreases pausing to enhance nucleosome remodeling by CSB", Nucleic Acids Research (2017).
담당부서연구지원과 (02) 880-5659